Ocular changes in patients undergoing long-term desferrioxamine treatment.

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Ocular changes in patients undergoing long-term desferrioxamine treatment.

In a group of young patients with thalassaemia and iron overload treated by subcutaneous infusions of desferrioxamine we have found a number of minor alterations in retinal function. The incidence of such changes is not related to drug dosage or to ferritin level but to abnormality of the extended glucose tolerance test.

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Fourteen rabbits received an intravitreal iron foreign body and were treated with desferrioxamine. Their electroretinographic (ERG) values were recorded and compared with those of an untreated group. With desferrioxamine treatment a delay of the siderotic damage and preservation of better ERG potentials is observed.

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1984

ISSN: 0007-1161

DOI: 10.1136/bjo.68.12.873